ANTAGONISM OF THE PROSTAGLANDIN D2 RECEPTOR CRTH2 ATTENUATES ASTHMA PATHOLOGY IN MOUSE EOSINOPHILIC AIRWAY INFLAMMATION

Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation

Abstract Background Mast cell-derived prostaglandin D2 (PGD2), may contribute to eosinophilic inflammation and mucus production in allergic asthma.Chemoattractant receptor homologous molecule expressed on TH2 cells (CRTH2), a high affinity receptor for prostaglandin D2, mediates trafficking of TH2-cells, mast cells, and eosinophils to inflammatory

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Relationship of oral hygiene status and practices with oral lesions in a group of HIV positive patients in Lagos, Nigeria

Objective: The oral health of HIV positive patients may be compromised because of their depressed immunity and may increase their risk of developing some oral lesions.This study was carried out to assess the relationship of the oral hygiene status and practices with oral lesions in HIV positive patients at a dedicated HIV clinic in Nigeria.Method:

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